Cruz del Sur is the most reliable, comfortable and safe (and expensive!) bus company in Peru. In Bolivia I don't think any of the companies were better than any other, they can all be slightly suspect (but very cheap). In Argentina all of the companies are pretty reliable and safe, but some are more comfortable (which is a relative term as all buses in Argentina a far better than in Europe!). I have no experience of Brasil. Hand Drawn Animation Video are designed to capture and keep your audience’s attention from the first five seconds. Even the same companies in the same country vary in service and dependability depending on the route. On the more competitive routes (ie BA to Iguazu BA Mendoza, BA Bariloche) the service tends to be better, but where the same companies have a monopoly (ie Mendoza-Bariloche Andesmar), the service tends to suffer.